Source Monitoring Déficit in Neuropsychiatric Population
ConditionPsychiatric Disorder
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorHôpital le Vinatier
About this trial
the investigators will measure source-monitoring ability in patients with several neuropsychiatric condition and in healthy controls appaired in age, sex and educational level. Source-monitoring will be measured thanks to internal- and reality-monitoring informatic tasks.The investigators hypothesized patients with fronto-temporal abnormalities would show more marked deficits than patients with only frontal abnormalities.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Subjects who gave their free and informed consent;
Men and women;
Aged 18 to 80;
Having normal or corrected vision;
Disqualifiers
Inadmissibility of the consent or refusal of the subject.
Patients under guardianship
Trial design
Design model
Parallel
Treatments tested in this trial
Monitoring source test
Other interventionInternal- and external-monitoring correct responses and inversions
Treatment groups
300 Participants
are divided into 2 treatment groupsGroup A: Patients with with neuropsychiatric conditionsExperimental treatment 1 intervention
Group B: Healthy subjectsActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
measure source memory performance
in patients with neuropsychiatric disorders with or without temporal involvement (pre-dementia Alzheimer's disease, Alzheimer's disease - AD, fronto-temporal dementia - DFT, Lewy body dementia - DCL and bipolar disorder - TBP) and healthy volunteers matched in age, gender, and level of education.
Time frame
one yearSecondary outcomes
1
measure the recognition of distractors
words not presented during the source monitoring test phase but presented during the recall phase. This measure will allow us to avoid that a disturbance invading the working memory or attentional capacities does not compromise the good realization of the task.
Time frame
one yearSponsors and contacts
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Source ClinicalTrials.gov