About this trial
Comorbid Childhood Apraxia of Speech (CAS) may be one factor that limits speech development in some minimally verbal children with autism. CAS is a disorder affecting speech movement planning. This study tests whether CAS-specific treatment, appropriately modified for minimally verbal children with autism, improves their speech.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Meets criteria for Autism Spectrum Disorder
Able to correctly repeat at least 2 syllables
Meets criteria for Childhood Apraxia of Speech
Lives in an environment where child is exposed to English at least 50% of the time
Disqualifiers
Poorly controlled seizures
Factors such as blindness or deafness that contribute to minimally verbal status
Lives in an environment where English is not spoken at least 50% of the time
Child experiences behavioral challenges that preclude participation in the study
Trial design
Single group
Treatments tested in this trial
CAS Treatment for Minimally Verbal Children with Autism
BehavioralTreatment involves principles of motor learning embedded in a naturalistic developmental milieu
Treatment groups
Trial outcomes
Primary outcomes
Attempts Correct
Number or percent of target items that were produced correctly
Phonemes Correct
Number or percent of phonemes (vowels, consonants) in the target items that were produced correctly
Secondary outcomes
Lip aperture movement variability
Amount of variability in lip opening area during production of multiple attempts at the same target
Phoneme distinctiveness
Acoustic distinctiveness of different phonemes
Sponsors and contacts
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