Spinal Neurorehabilitation for Veterans With SCI

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorVA Office of Research and Development

About this trial

Chronic spinal cord injury (SCI) is a debilitating disorder in Veterans and the broader U.S. population that does not have a cure. Veterans with severe SCI demonstrate permanent loss of sensory and motor function below their injury resulting in decreased quality of life and independence. Recently, electrical spinal neuromodulation has emerged as a potential approach to restore voluntary motor function and locomotion in persons with chronic SCI. However, spinal neuromodulation has yet to translate to clinical use due to small sample sizes in research studies and a lack of information on which patients would benefit. Here, the investigators propose a novel approach to evaluate the priorities and barriers faced by Veterans with SCI to use spinal neuromodulation, understand the neural connections remaining in Veterans with severe SCI, and determine potential functional improvements using non-invasive spinal neuromodulation technology. This research represents the first step towards deploying techniques that could dramatically improve function and quality of life for Veterans with SCI.

Eligibility criteria

Qualifiers

All participants must be able to independently read and understand study information materials necessary to ensure informed consent.

All participants must have a chronic spinal cord injury occurring >1 year prior to study enrollment.

Ability to follow simple commands in English.

Disqualifiers

Contraindications to the use of external magnetic or electrical stimulation (e.g., epilepsy, intracranial metal, implanted electrosensitive device, etc.)

Significant neurological comorbidities that may affect neurophysiological recordings

Functional disability prior to spinal cord injury

Visual or auditory disorders limiting ability to participate in study procedures

Trial design

Treatments tested in this trial

  • Neurophysiological and anatomical testing
  • Transcutaneous Spinal Stimulation

Treatment groups

40 Participants
are divided into 1 treatment group