About this trial
This observational study of aims to test whether and how the results of GLIM change when using different approaches and methods to carry out its components.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age of 18+ years
Able and willing to sign the consent form
Inpatients of the Tartu University Hospital
Admitted within 72 hours before enrolment
Disqualifiers
Age of <18 years
Inability or refusal to sign the consent form
Pregnant or lactating women
More than 72 hours passed since admission
Trial population
Inpatients of day patients admitted to the Tartu University Hospital.
Trial design
Cohort
Prospective
Treatments tested in this trial
Nutrition screening and assessment
Diagnostic testThe patient is interviewed for changes in body weight in the last six months and food intake in the last two weeks. The investigator evaluates the patient's diet, symptoms related to their nutritional status, and functional capacity according to the Subjective Global Assessment (SGA). The SGA tool itself is completed by the researcher. Height and weight of the patient are measured, if not yet recorded, and BMI is calculated. The patient's muscle mass is measured using mid-upper arm circumference (MUAC), calf circumference (CC) and bioelectrical impedance (BIA), and their muscle function assessed using hand grip strength.
Treatment groups
Trial outcomes
Primary outcomes
Subjective Global Assessment (SGA) defined malnutrition
Subjective Global Assessment (SGA) can be considered a method that is close to a "gold standard" for malnutrition assessment. Therefore, the study will analyse how different approaches to screening and muscle mass measurement affect the performance of GLIM in detecting Subjective Global Assessment (SGA) defined malnutrition.
One-year mortality
One year after the data collection, we will look at the patient records to collect the 1-year mortality data. This will give information about whether and how different approaches to components of GLIM affect its ability to predict one-year mortality.
Computed tomography (CT) defined muscle mass
One of the GLIM criteria is "reduced muscle mass", and this study will investigate how muscle mass measured with simpler methods compares against muscle mass measured with CT.
DEXA defined muscle mass
One of the GLIM criteria is "reduced muscle mass", and this study will investigate how muscle mass measured with simpler methods compares against muscle mass measured with DEXA.
Secondary outcomes
Bioelectrical impedance (BIA) defined muscle mass
One of the GLIM criteria is "reduced muscle mass", and this study will investigate how muscle mass measured with simpler methods compares against muscle mass measured with BIA.
Sponsors and contacts
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University of Tartu
Lead sponsor
Tartu University Hospital
Collaborator