Stimulation of the Larynx to Treat Unexplained Chronic Cough

ConditionCough

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-88

SponsorUniversity of Minnesota

About this trial

Researchers will test the effect of non-invasive vibrotactile stimulation of the larynx on symptom severity of unexplained chronic cough.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults aged 18-88

>8 weeks of cough

Cough visual analogue scale (VAS): Rating of 30 or greater on a 0-100 cough severity scale

Ability to provide informed consent and independently complete questionnaires

Disqualifiers

Electronic implants (e.g., pacemaker)

Currently doing speech therapy for cough

Contraindications to safe or effective VTS device use

No regular access to wifi internet Neuromuscular impairment that may affect cough/laryngeal sensation and/or function (e.g., multiple system atrophy, Parkinson, CVA, vocal fold paralysis or paresis)

Trial design

Design model

Single group

Treatments tested in this trial

Vibrotactile Stimulation
Device
Small electric motors, similar to a vibrating cell phone or gaming joystick, deliver vibration to the throat. Participants will assess cough symptoms throughout the study period.

Treatment groups

60 Participants

are divided into 1 treatment group

Group A: Vibrotactile StimulationExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

Assess usability of VTS device

% of participants indicating agree or strongly agree with statements of usability

Time frame

3-7 weeks

Impact of VTS on cough symptoms

Pre-post comparison of LCQ scores

Time frame

3-7 weeks

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Minnesota

Lead sponsor

Source ClinicalTrials.gov

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