Strength Tracking From Wall Tichness Over Aortic Biomechanics (STORM)
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorIRCCS Policlinico S. Donato
About this trial
The aim of the study is to analyse the resected portion of aneurysmatic ascending aorta in order to assess its strength to rupture, standardise the various measurements performed within the lab and try to correlate these qualitative results with quantitative results (regarding aortic diameter, valve morphology and aortic wall thickness).
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients undergoing cardiac surgery for either aortic root and/or ascending aortic aneurysms; • Patients that have received, understood and signed the written informed consent for this study.
Disqualifiers
Patients that have already undergone previous cardiac surgery; • Patients that present with acute aortic pathologies, such as acute aortic dissection or intramural hematoma.
Trial population
Patients undergoing cardiac surgery for ascending or aortic root aneurysms.
Trial design
Design model
Cohort
Time perspective
Cross-sectional
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
Strength to rupture
Define the strength to rupture of the removed aortic segments and its relation with the circumferential and longitudinal direction along the aortic axis.
Time frame
During laboratory testingSecondary outcomes
1
Evaluate aortic characteristics
Evaluate multiple characteristics of the surgically excised pathologically enlarged aortic segments: shape alteration, tensile strength, elasticity capacity.
Time frame
From surgery to laboratory testingOther outcomes
1
Standardize mechanical measurements
Assess from a methodological point of view the various aspects and results of the different test and identify the ideal testing method (uniaxial vs biaxial)
Time frame
During laboratory testingSponsors and contacts
Click on the lead sponsor to view all of their trials.
IRCCS Policlinico S. Donato
Lead sponsor
University of Pavia
Collaborator
Source ClinicalTrials.gov