Stress and Resilience

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-30
SponsorUniversity of Washington

About this trial

Alcohol and cannabis are the most misused psychoactive substances in the United States. The proposed research examines how personally relevant stressful experiences may lead to alcohol and cannabis use. The proposed research is also designed to identify possible targets for prevention and treatment efforts to help reduce drug use.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Of Afro-descent

Proficient in English

Alcohol and/or cannabis use at least 2-3 times in the past month

Endorse having used alcohol and/or cannabis to cope

Disqualifiers

Having participated in similar studies by the research team

Obtain cut-off scores on scale items indicating possible loss of control and needing to cut down or quit alcohol and/or cannabis use

In or seeking treatment for alcohol and/or cannabis use disorder

Trial design

Design model

Parallel

Treatments tested in this trial

  • Direct Interpersonal Exchange

    Behavioral

    Simulated a negative personally relevant interpersonal experience that is received directly from a perpetrator, commonly experienced in everyday lives

  • Vicarious Interpersonal Exchange

    Behavioral

    Hearing or observing a negative personally relevant interpersonal experience that is reported by another person of the same background

  • Daily Hassles

    Behavioral

    Day-to-day stressors associated with school, work, finances

Treatment groups

456 Participants
are divided into 3 treatment groups
Group A: Direct Interpersonal ExchangeExperimental treatment 1 intervention
Group B: Vicarious Interpersonal ExchangeExperimental treatment 1 intervention
Group C: Daily HasslesPlacebo comparator 1 intervention

Trial outcomes

Primary outcomes

1

Momentary Alcohol and/or Cannabis Craving

Momentary Alcohol and Cannabis Craving Scale will be administered (adapted from the Momentary Cannabis Craving Scale; Davis et al., 2024) immediately after the intervention. Mean scores will range from 1 to 7, with higher scores indicating greater momentary craving.

Time frame
Immediately after the intervention (i.e., within 1 minute)
2

Duration of Alcohol and Cannabis Intoxication

Self-reported number of hours of intoxication within 48 hours after the intervention

Time frame
48 Hours Post-Intervention

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

University of Washington

Lead sponsor

National Institute on Drug Abuse (NIDA)

Collaborator