Stroke Volume-based Fluid Resuscitation in AP
ConditionAcute Pancreatitis (AP)
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorUniversity of Southern California
About this trial
The SUSTAIN Trial is a randomized control trial that allows for the control of aggressive hydration that is currently used in an inpatient setting, which can result is fluid overload in certain patients. With the impression that changes in stroke volume in individual patient will further improve the outcome.
Eligibility criteria
Qualifiers
Patients between the age of 18-75
Predicted moderate and severe acute pancreatitis, which will be defined by the presence of SIRs, within 24 hours of enrollment
Disqualifiers
Patients with the inability to preform a straight leg raise (i.e amputation)
Patients with high risk of adverse event related to fluid resuscitation
NYHA Class >= II Heart Failure
Child's B and C Cirrhosis
Trial design
Treatments tested in this trial
- Lactated Ringer's
- Lactated Ringers Stroke Volume Based Dosing
Treatment groups
80 Participants
are divided into 2 treatment groupsSponsors and collaborators
University of Southern California
Lead sponsor
Ohio State University
Collaborator
Source ClinicalTrials.gov