SV and IVC Collapsibility Index to Predict Postinduction Hypotension
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age40-70
SponsorAin Shams University
About this trial
Postinduction hypotension (PIH) is a frequent complication during general anesthesia. This study aims to compare the predictive effectiveness and diagnostic accuracy of stroke volume (SV) measured via left ventricular outflow tract velocity time integral (LVOT-VTI) versus the inferior vena cava collapsibility index (IVC-CI) using transthoracic echocardiography. The assessment will be conducted in adult patients with intestinal obstruction undergoing exploratory abdominal surgery under general anesthesia.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Adult patients with intestinal bowel obstruction undergoing exploratory abdominal surgery under general anesthesia.
Age 40 to 70 years old.
Body Mass Index (BMI) = 18 to 25 kg/m2.
American Society of Anesthesiologists (ASA) physical status grade I or II.
Disqualifiers
American Society of Anesthesiologists (ASA) physical status grade >= III.
Patients in whom the IVC cannot be visualized or patients with poor echogenicity.
Patients with hemodynamic instability.
Patients with vascular, respiratory, or cardiac diseases (e.g., cardiomyopathy, heart valve disease, arrhythmia, or bad exercise tolerance).
Trial population
Adult patients diagnosed with intestinal obstruction scheduled for exploratory abdominal surgery under general anesthesia at Ain-Shams University Hospitals.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
Diagnostic accuracy of Stroke Volume (SV) to predict post-induction hypotension.
Area under the receiver operating characteristic curve (AUC) of stroke volume measured via left ventricular outflow tract velocity-time integral (LVOT-VTI) as a predictor of post-induction hypotension.
Time frame
Baseline (pre-induction) and immediately post-induction.2
Diagnostic accuracy of Inferior Vena Cava Collapsibility Index (IVC-CI) to predict post-induction hypotension.
Area under the receiver operating characteristic curve (AUC) of inferior vena cava collapsibility index measured via transthoracic echocardiography (TTE) as a predictor of post-induction hypotension.
Time frame
Baseline (pre-induction) and immediately post-induction.Secondary outcomes
1
Incidence of Post-Induction Hypotension
Assessment of the proportion of patients who develop post-induction hypotension, defined as SBP decrease \> 30%, MAP decrease \> 20% from baseline, or absolute SBP \< 90 mmHg and MAP \< 60 mmHg.
Time frame
Within 3 minutes following induction of general anesthesia.2
Length of Hospital Stay Length of Hospital Stay
Total duration of hospitalization from the day of surgery until discharge.
Time frame
From date of surgery until hospital discharge (up to 9 months).3
Time to Recovery from Post-Anesthesia Care Unit (PACU) Time to Recovery from Post-Anesthesia Care Unit (PACU)
Time elapsed from patient admission to the PACU until meeting discharge criteria. Time elapsed from patient admission to the PACU until meeting discharge criteria.
Time frame
Intraoperative / immediate postoperative period until PACU discharge (up to 24 hours).Locations
Sponsors and contacts
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Source ClinicalTrials.gov
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