This is a prospective multicenter observational study on medullary thyroid cancer , aiming to investigate the correlation of stromal desmoplastic reaction with tumor aggressiveness.
Patients who underwent thyroidectomy for medullary thyroid cancer (total thyroidectomy) +/- central/lateral neck dissection
Sporadic medullary thyroid cancer
Age < 18 years
Hereditary medullary thyroid cancer cases
Patients that do not undergo central or lateral lymph node dissection
Patient unwillingness to participate in this study
Patients with medullary thyroid cancer that will undergo surgery as curative method
Cohort
Prospective
lobectomy with lymph node dissection
Procedure/SurgeryThis operation is the one suggested by the guidelines for medullary thyroid cancer
Number of patients with absence of Desmoplastic stromal reaction and metastatic lymph node in central and lateral compartment
Number of patients with absence of Desmoplastic stromal reaction and metastatic lymph node in central and lateral compartment
Factors like baseline calcitonin levels, extrathyroidal extension, lymphovascular and capsular invasion that correlate with lymph node metastasis in medullary thyroid cancer
Factors like baseline calcitonin levels, extrathyroidal extension, lymphovascular and capsular invasion that correlate with lymph node metastasis in medullary thyroid cancer
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Aristotle University Of Thessaloniki
Lead sponsor
University of Cagliari
Collaborator
University of Pisa
Collaborator
Universita di Verona
Collaborator
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Collaborator
This trial is not recruiting at the moment. You can still explore other options:
