This study investigates the clinical and structural predictors of long-term cognitive impairment in patients who underwent microsurgical clipping for aneurysmal subarachnoid hemorrhage. Using a retrospective cohort with prospective neuropsychological and MRI assessments, it aims to identify factors associated with late cognitive deficits and improve prognostic stratification, rehabilitation planning, and long-term patient care.
Age ≥18 years at the time of aSAH.
Treatment by microsurgical clipping of a ruptured cerebral aneurysm.
Survival until study recruitment.
Ability to understand and sign informed consent.
Non-aneurysmal subarachnoid hemorrhage.
Exclusively endovascular treatment.
Previous diagnosis of dementia.
Severe neurological or psychiatric disorders unrelated to aSAH with significant cognitive impact.
University of Campinas, Brazil
Lead sponsor
Hospital de Clinicas da Unicamp - SP
Collaborator