29.3% of bacteremias in intensive care units (ICU) are linked to vascular devices, including 7.7% to arterial catheters, with an influence on both morbility and mortality.
It is now accepted that biofilm as a role on bacterial development on inner surface of vascular devices but there is yet a lack of clinical relevant data documenting a causal relation between biofilm formation and bacteremias.
The investigators assume that a better structural and microbiological characterization of arterial catheter biofilm in ICU patients could help preventing bacteremias or have a more specific treatment when it appears.
Patient or relative informed of the study and having declared their non-objection
Patient over 18 years old
Patient hospitalized in ICU with an arterial catheter
Patient unable to express consent
Patient whose collection of the arterial catheter is impossible or for whom storage at 4°C is impossible
Patient with arterial catheter removed outside the usual procedure of the ICU
Patient admitted in ICU with an arterial catheter already in place
Patient over 18 years of age with artherial catheter more than 2 calendar days
Other
Prospective
OCT-BIO-KTA cohort
Other interventionDynamic full-field optical coherence tomography (D-FF-OCT) analysis of arterial catheter sections before microbiological analysis of catheter biofilm
Biofilm structure type (ribbon-shaped or mushroom-shaped), measured with D-FF-OCT
Provide a better understanding of the relation between structural and microbiological characterization of artherial catheter biofilm in ICU patients using D-FF-OCT
Bacterial or fungal indentification
Identification and enumeration of species - whether bacterial or fungal - by mass spectrometry from culture in agar medium of biofilm samples
Biofilm thickness, measured with D-FF-OCT
Provide a better understanding of the relation between thickness and microbiological characterization of artherial catheter biofilm in ICU patients using D-FF-OCT
Biofilm dynamic signal distribution, measured with D-FF-OCT
Provide a better understanding of the relation between dynamic signal distribution and microbiological characterization of artherial catheter biofilm in ICU patients using D-FF-OCT
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Centre Hospitalier William Morey - Chalon sur Saône
Lead sponsor
Centre Hospitalier Universitaire Dijon
Collaborator
Centre Hospitalier Macon
Collaborator
