Study About Contrast Media
ConditionSmall Bowel Obstruction
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Tartu
About this trial
Patients hospitalized with adhesive small bowel obstruction (SBO) are randomized to 2 study groups at admission after signing an informed consent form. Water-soluble contrast media (CM) will be administered after 4 or after 24 hours of nasogastric- tube decompression.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients 18 years or older
Adhesive small bowel obstruction diagnosed (clinical, laboratory and radiologic evaluation
No peritonitis present, no need for an emergent surgery
Patients sign an informed consent
Disqualifiers
Patients younger than 18 yeas
Patients with mechanical small bowel obstruction caused by incarcerated hernias
Patients with mechanical small bowel obstruction caused by carcinomatosis
Patients with paralytic small bowel obstruction
Trial design
Design model
Parallel
Treatments tested in this trial
Effect on contrast media depending on the time of its administratsion
Other interventionCM is a common practice when it comes to the management of small bowel obstruction. However there is no consensus as when it should be administered
Treatment groups
120 Participants
are divided into 2 treatment groupsGroup A: Contrast media 4 hoursActive comparator 1 intervention
Group B: Contrast media 24 hoursActive comparator 1 intervention
Trial outcomes
Primary outcomes
1
SBO resolution
SBO resolution with conservative measures * passing gas * bowel movement * CM in the colon on the X-ray
Time frame
Period of hospitalization- approximately 5 daysSponsors and contacts
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University of Tartu
Lead sponsor
North Estonia Medical Centre
Collaborator
Source ClinicalTrials.gov