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Study of Auditory Perception After Progressive Exposure to Aversive Sounds in People With Misophonia

ConditionMisophonia
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorInstitut Pasteur

About this trial

The primary objective of the project is to characterise and measure the auditory perception of subjects with misophonia compared with the auditory perception of control subjects.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Obtain oral consent from the participant after receiving information about the study,

Be 18 years or older on the day of inclusion,

Be fluent in French (spoken and written),

Have no known hearing loss, verified by pure tone audiometry.

Disqualifiers

Bear the after-effects of an ear infection and/or have a history of an ENT disease that permanently affects hearing or balance (vestibular schwannoma, Ménière's disease, sudden or fluctuating deafness, congenital hypoacusis),

Be under guardianship,

deprived of liberty by judicial or administrative decision, or subject to legal protection.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Psychoacoustic test

    Behavioral

    Natural sounds will be presented at different decibels (dB), and the subject will be asked to rate the pleasantness/unpleasantness of the sound heard on a visual analogue scale, as well as the loudness (subjective intensity) of the sound heard.

  • semi-structured interviews

    Other intervention

    interview, designed under the supervision of a psychologist and using the methodology of micro-phenomenological interviews the aim of these interviews is to gain access to the participants' experiences, as they describe them in the first person, during misophonic episodes

  • Exposure to unpleasant sounds

    Other intervention

    Home exposure is a practice whereby participants voluntarily subject themselves to SMs in a controlled environment. Participants will be asked to complete two tasks: firstly, they will have to expose themselves to all 10 sounds at least twice a week; secondly, they will have to record the annoyance felt for each sound and the subjective loudness (loudness) of each SM using VAS.

Treatment groups

110 Participants
are divided into 2 treatment groups
Group A: Control groupActive comparator 2 interventions
Group B: Misophonia groupExperimental treatment 3 interventions

Trial outcomes

Primary outcomes

1

score on a visual analogue scale from 0 (pleasant sound) to 10 (unpleasant sound)

sounds will be presented at different decibels and the subject will be asked to rate the pleasantness/unpleasantness of the sound on a visual analogue scale

Time frame
1 week after enrollment
2

score on a visual analogue scale from 0 (very low intensity) to 10 (extremely intense)

sounds will be presented at different decibels and the subject will be asked to rate the intensity of the sound on a visual analogue scale

Time frame
1 week after enrollment

Secondary outcomes

1

Measuring the consistency of the psychoacoustic test

consistency measured by calculating Cronbach's alpha coefficient

Time frame
1 week after enrollement
2

the number of redundant themes in the semi-structured interviews

the interviews consist of open-ended questions covering different aspects of the experiences of misophone subjects

Time frame
1 month after enrollment
3

score on a visual analogue scale from 0 (very little discomfort) to 10 (extreme discomfort)

Time frame
1 month after enrollment and 2 months after enrollment

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Institut Pasteur

Lead sponsor

Institut de l'Audition

Collaborator

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: