Study of Corneal Biomechanics in Glaucoma Patients Using Brillouin Microscopy

ConditionGlaucoma
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity of Maryland, Baltimore

About this trial

This pilot study evaluates the biomechanical properties of the cornea in glaucoma patients using Brillouin microscopy, a non-contact imaging technique. The study aims to compare corneal stiffness between patients with normal-tension glaucoma, high-tension glaucoma, and healthy controls, and to assess changes in corneal biomechanics following intraocular pressure (IOP)-lowering treatment. The goal is to determine whether Brillouin-derived biomechanical measurements can serve as biomarkers for glaucoma risk and progression.

Eligibility criteria

Qualifiers

None

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Prostaglandin Analogue -Containing IOP-Lowering Therapy
  • Beta Blocker
  • Brillouin Microscopy

Treatment groups

60 Participants
are divided into 3 treatment groups

Sponsors and collaborators

University of Maryland, Baltimore

Lead sponsor

National Eye Institute (NEI)

Collaborator