Study of Functional Decline and Care Pathways in Neurosurgical Patients Over 65 Years of Age

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65+
SponsorUniversity Hospital, Toulouse

About this trial

The GENEUS 1 study addresses this gap by characterizing the real-world profiles, outcomes, and care pathways of adults aged 65 years and older hospitalized in neurosurgery across France, Spain, and Portugal. This project represents the first multicentre, transnational initiative to integrate geriatric principles into neurosurgical practice and to evaluate both clinical and economic outcomes in this population.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial population

Patients aged 65 years or older admitted for neurosurgical intervention, for whom follow-up for 3 months is possible given their cognitive status and life expectancy, and who agrees to the retrieval of their hospital clinical and health economic data during the year following their discharge from the hospital

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

The evolution of functional autonomy between baseline and 3 months post-discharge

The change is measured using validated geriatric scale Basic Activities of Daily Living Functional decline will be defined as any clinically significant decrease in ADL score compared with baseline. The change will be expressed both as a continuous variable (score variation) and as a categorical outcome (improved / stable / declined autonomy). This criterion captures the short-term functional trajectory of older adults after a neurosurgical hospitalization and serves as the main indicator of care effectiveness and adaptation to geriatric needs.

Time frame
between baseline and 3-month after discharge

Secondary outcomes

1

Length of hospital stay

Number of days from admission to discharge.

Time frame
baseline until the day of hospital discharge
2

Postoperative complications

Complications classified according to the Clavien-Dindo scale

Time frame
the day of the hospital discharge
3

Daily living

scoring of the scale : instrumental activities of daily living (IADL) score 0 is the worst, score 8 is the best autonomy

Time frame
baseline, the day of hospital discharge and 3-month after discharge
4

Composite criteria of Cognitive status and delirium composed of 3 criteriaes

first criteria : score of the scale of Sclan and Reisberg - score is between 1 and 7 - 1 is the better and 7 the worst second criteria : score of the test for delirium \& cognitive impairment (4AT) - the score is beetwen 0 and 4 - 0 is the better and 4 the worst third criteria : Mini Mental State Examination

Time frame
baseline and the day of hospital discharge

Other outcomes

Sponsors and contacts

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