Study of Platelet Population Changes Under Circulatory Support With ECMO
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital, Strasbourg, France
About this trial
Advances in flow cytometry techniques have led to a better understanding of platelet phenotypes and have revealed the existence of four major platelet populations with distinct functional properties (native, proaggregating, procoagulating, or apoptotic). These phenotypes have a significant impact on the hemostatic capacity of blood platelets, and a proportional change in these populations during ECMO treatment could, at least in part, contribute to the observed complications.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Adult patient (≥18 years) treated in one of the intensive care units of the Anesthesia and Intensive Care Department at Strasbourg University Hospital.
Implanted with veno-arterial or veno-venous ECMO within the previous 24 hours.
Disqualifiers
Subject who has expressed their opposition to participating in the study.
Subject under legal protection.
Subject under guardianship or curatorship.
Trial population
\- Adult patient (≥18 years) treated in one of the intensive care units of the Anesthesia and Intensive Care Department at Strasbourg University Hospital and implanted with veno-arterial or veno-venous ECMO within the previous 24 hours.
Trial design
Design model
Case-only
Time perspective
Retrospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
Proportional Changes in the Different Platelet Populations (native, proaggregating, procoagulant, or apoptotic)
Proportional Changes in the Different Platelet Populations (native, proaggregating, procoagulant, or apoptotic) on Days 1, 3, and 7 after the initiation of ECMO treatment.
Time frame
Days 1, 3, and 7 after the initiation of ECMO treatment.Sponsors and contacts
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Source ClinicalTrials.gov