Evaluation of the level of hypoxemia during the occurrence of cardiocirculatory arrest during a Maastricht III organ donation procedure.
Patient over 18 years of age
Organ donation procedure initiated in accordance with the legislation and procedures in force in France for the Maastricht III category
No opposition formulated by the relative to the patient's participation in the study
Patient registered on the national register of refusals or living refusal of donation
Pregnant or breast-feeding women
Patients under guardianship, curatorship or legal protection
Medical contraindication to organ donation according to the recommendations of the Agence de Biomédecine currently in force in France
Patients who may be candidates for an organ donation procedure in the event of death in intensive care following the implementation of a procedure to discontinue active therapies.
Case-only
Prospective
blood sampling
Other intervention* The first sample is taken at the start of the therapeutic stop. * The second sample is taken when the mean arterial pressure drops to 45mmHg. * The third sample is taken when circulatory arrest occurs. * The fourth sample is taken at the start of extracorporeal circulation. These four samples will be destroyed at the end of the study.
PaO2 level
PaO2 level and its 95% confidence interval in the event of circulatory cardiac arrest, defined as a pulse pressure below 5 mmHg, during a Maastricht III procedure.
Spo2 Level
Define the level of Spo2 (and its 95% confidence interval) at the time of cardiocirculatory arrest during a Maastricht III procedure.
Time between occurrence of first episode of pulsed oxygen saturation below 95% and onset of cardiocirculatory arrest
Define the time (and its 95% confidence interval) between the occurrence of the first first episode of pulsed oxygen saturation below 95% and the onset of cardio-circulatory arrest defined by absence of pulsed pressure below 5 mmHg.
Correlation between the rate of delayed recovery of renal function in the recipient and the presence of hypoxemia at the time of cardiocirculatory arrest in the donor.
Delayed recovery of renal function will be confirmed if the recipient undergoes dialysis within the first 7 days after transplantation. Hypoxemia is defined as a PaO2 less than or equal to the median value.
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