Health TrialsbyHealthPanel

Study the Effect of Plant-based Beverage Consumption on the Gut Microbiome in Healthy Adults

ConditionsPlant-based MilkGastrointestinal Microbiome
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorLund University

About this trial

The goal of this intervention study is to analyse the microbiota composition after the plant-based beverage consumption. The main questions are to evaluate if the plant-based beverage can have a beneficial effect on the gut microbiota. Participants will consume different plant-based beverages for two weeks, and microbiota will be analysed. Researchers will compare the microbiota composition before and after consumption.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

None

Disqualifiers

Must not be diagnosed with gastrointestinal diseases, autoimmune diseases or have diseases or medications that cause immune deficiency, such as MS, type 1 diabetes, cancer or HIV

must not take antibiotics during the study period

must not have a milk protein allergy

Trial design

Design model

Parallel

Treatments tested in this trial

  • plant-based beverage

    Dietary supplement

    Participants will consume the assigned plant-based beverages for two weeks.

Treatment groups

60 Participants
are divided into 2 treatment groups
Group A: Active groupActive comparator 1 intervention
Group B: Experimental groupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Change in gut microbiome alpha diversity

Gut microbiome alpha diversity will be assessed using 16S rRNA gene sequencing and quantified using alpha diversity indices (e.g., Shannon diversity index).

Time frame
up to 24 weeks
2

Change in gut microbiome beta diversity

Gut microbiome beta diversity will be assessed using 16S rRNA gene sequencing by comparing community composition between samples using beta diversity distance metrics (e.g., Bray-Curtis dissimilarity or UniFrac distances).

Time frame
Upto 24 weeks

Secondary outcomes

1

Change in the relative abundance of gut bacterial taxa

The relative abundance of bacterial taxa identified by 16S rRNA gene sequencing will be compared between study groups and over time.

Time frame
Baseline to Week 24

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Lund University

Lead sponsor

Source ClinicalTrials.gov
Apply now