Subthalamic Nucleus, Akinesia and Parkinson's Disease

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-70
SponsorInstitut National de la Santé Et de la Recherche Médicale, France

About this trial

This program aims to understand the role of the subthalamic nucleus in the control of the movement in healthy humans and patients with Parkinson's disease, how the STN dysfunction contributes to akinesia and how the STN stimulation improves motor signs in PD patients .

Eligibility criteria

Qualifiers

Diagnosis of idiopathic Parkinson's disease (according to the criteria of the United Kingdom Parkinson's Disease Society Brain Bank)

Age between 18 and 70;

Motor complications in the form of fluctuations in motor state or dyskinesias induced by dopaminergic therapy, despite medical treatment optimum;

Other medical conditions that are stable or do not interfere with the procedure proposed;

Disqualifiers

None

Trial design

Treatments tested in this trial

  • Bilateral subthalamic stimulation

Treatment groups

180 Participants
are divided into 1 treatment group