About this trial
Depression is disabling and affects one in five Veterans. VA's Primary Care-Mental health Integration (PCMHI) enables specialists to support medication treatment in primary care, but timely and sufficient access to psychotherapy is unattainable despite Veteran preference for psychotherapy. This study aims to close the gap in psychotherapy access for VA primary care patients with depression by adapting PCMHI collaborative care models to improve uptake of peer-supported computerized cognitive behavioral therapy (cCBT).
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Must be enrolled in the VHA and currently receiving primary care services at VA Los Angeles or San Diego
Have access to computer (mobile or desktop), internet, telephone, and email
Able to read English text on a computer screen
Score 10 or higher on the PHQ-9
Disqualifiers
Have moderate-high suicide risk (e.g. suicide flag) or active suicidality
Have other serious mental illness (e.g. bipolar disorder, psychosis)
Have medical disorder that would prevent/ interfere with participation (e.g. dementia/cognitive impairment, terminal illness)
Trial design
Parallel
Treatments tested in this trial
Enhanced Usual Care (EUC)
BehavioralEnhanced usual care includes all the usual depression care at the VA and access to an online therapy program with no peer support sessions. The online therapy program offered consists of several modules for depression care, specifically tailored for Veterans.
Supported Online Self-help for Depression (SOS-Depression)
BehavioralSupported Online Self-help for Depression (SOS-Depression) includes all the usual depression care at the VA and access to an online therapy program with support sessions with a peer. The online therapy program consists of several modules for depression care, specifically tailored for Veterans.
Treatment groups
Trial outcomes
Primary outcomes
Patient Health Questionnaire (PHQ-9)
The Patient Health Questionnaire (PHQ-9) is a scale commonly used to measure and categorize depression symptoms. It is already administered as part of routine primary care at our study site. The minimum score is 0, the maximum is 27. A higher score indicates a worse outcome (i.e. more severe depression symptoms).
Secondary outcomes
Behavioral Activation for Depression Scale (BADS-SF)
The 9-item Behavioral Activation for Depression Scale (BADS-SF) will also be used to examine behavioral activation as an intermediary to depression symptomatology outcomes. The minimum score is 0, the maximum is 54. Higher scores indicate a better outcome (i.e., higher activation).
Generalized Anxiety Disorder (GAD-7)
The 7-item Generalized Anxiety Disorder (GAD-7) is among the most commonly used and best validated anxiety measures in primary care settings. The minimum score is 0, the maximum is 21. Higher scores indicate a worse outcome (i.e., more severe anxiety). For reference: scores of 0-4=minimal anxiety, 5-9=mild anxiety, 10-14=moderate anxiety, and 15-21=severe anxiety.
World Health Organization Disability Assessment Schedule (WHODAS 2.0)
The World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) 12-item version is a brief self-report measure that will be used to assess functioning and disability across multiple domains of daily life. The minimum score is 0, and the maximum score is 48. Higher scores indicate greater disability.
Other outcomes
Treatment Engagement
Treatment engagement will be conceptualized as the number of cCBT sessions completed. A higher number indicates more cCBT sessions completed, but isn't indicative of a better or worse outcome.
Sponsors and contacts
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University of California, Los Angeles
Lead sponsor
San Diego Veterans Healthcare System
Collaborator
VA Greater Los Angeles Healthcare System
Collaborator
Congressionally Directed Medical Research Programs
Collaborator
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