SURgical Registry of ENDocarditis EuRope
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorUniversity Hospital, Essen
About this trial
This is a prospective, multicentric, european registry of patients with infective endocarditis undergoing cardiac surgery. Patient demographics, clinical data and laboratory values will be collected, as well as treatment outcomes at day 30, day 90 and 1-5 years after the intervention.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients with infective endocarditis (according to DUKE criteria) undergoing cardiac surgery
Age ≥18 years
Written informed consent
Disqualifiers
Age < 18 years
Missing declaration of consent
Current participation in another interventional trial
Trial population
Patients with infective endocarditis undergoing open heart surgery with cardio-pulmonary bypass
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Cardiac surgery
Procedure/SurgeryPatients with infective endocarditis undergoing open heart surgery
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
In-hospital mortality (all cause)
Overall mortality rate in-hospital, at day 30 or during index hospitalization
Time frame
30 days or during index hospitalization2
Mortality at long-term follow-up
at 1 to 5 years post-surgery
Time frame
1 to 5 yearsSecondary outcomes
1
MACCE
Major adverse cardiac and cerebrovascular event rate at day 30 or during index hospitalization. Composite of 1.) Cardiac events: (postoperative myocardial infarction, CPR, LCOS/heart failure, repeat cardiac surgery) and/or cerebrovascular events (postoperative stroke, TIA, intracranial hemorrhage)
Time frame
30 days or during index hospitalization2
MACCE at long term follow-up
Major adverse cardiac and cerebrovascular event rate at 1 to 5 years post-surgery
Time frame
1 to 5 years3
Sepsis accociated mortatilty
Sepsis accociated mortatilty at day 30 or during index hospitalization
Time frame
30 days or during index hospitalization4
Post-operative sepsis
Sepsis at day 30 or during index hospitalization
Time frame
30 days or during index hospitalizationSponsors and contacts
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Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: