Sustainable Implementation of the EXCEL Exercise Oncology Program Across Canada
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Calgary
About this trial
EXCEL will provide online and, where feasible, in-person exercise programs to individuals living with and beyond cancer (ILWBC). Research has shown that targeted programs that include tailored exercise prescriptions are more successful in helping individuals with chronic disease to incorporate physical activity and exercise into their daily routines. While ILWBC are advised by healthcare professionals (HCPs) to engage in exercise, there is a lack of cancer-specific exercise programs and cancer-trained exercise specialists in Canada, outside of the research setting. Considering the negative impact cancer and its treatments have on fitness and physical activity levels, community-based efforts towards improving access, uptake and maintenance of exercise programming are needed.
This study will evaluate the benefits of a community-based or online EXCEL exercise program for people living with and beyond cancer across Canada, using a streamlined intake process compared to the original EXCEL Study (HREBA.CC-20-0098, NCT04478851). This 8 to 12-week program (intervention) will be delivered in-person or over virtual platform. It includes twice weekly supervised exercise classes.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
have or had a diagnosis of cancer;
be 18 years or older;
be able to participate in low-intensity levels of activity, at minimum;
be pretreatment, or receiving active cancer treatment (i.e., surgery, systemic therapy and radiation therapy), have received cancer treatment within the past 3 years, or if beyond 3 years since treatment completion, have a referral from their healthcare team indicating they have side effects from cancer treatment or the cancer itself, that could be improved or managed with exercise;
Disqualifiers
does not or did not have a cancer diagnosis
is under the age of 18
is unable to participate in mild exercise, at minimum
is not pretreatment, or receiving active cancer treatment (i.e., surgery, systemic therapy and radiation therapy), has not received cancer treatment within the past 3 years, or if beyond 3 years since treatment completion, doesn't have side effects from cancer treatment or the cancer itself, that could be improved or managed with exercise
Trial design
Design model
Single group
Treatments tested in this trial
Group Exercise Classes
BehavioralParticipants will take part in a combination of aerobic, resistance, balance, and flexibility exercises delivered in a circuit-type class setting, twice weekly for a 8-12-week period (duration of intervention depends on scheduling logistics for the coordinating hubs and their spokes sites). The exercise sessions will be conducted in groups with a ratio of up to 15 participants per instructor. The program follows exercise progression principles (i.e., frequency, intensity, time, type, overload and progression) over the 8-12-weeks, with tailoring of any exercise to meet individual participant needs as required, in order to promote fitness and wellness benefits.
Treatment groups
740 Participants
are divided into 1 treatment groupGroup A: InterventionExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Physical Activity Level
The Modified Godin Leisure Time Exercise Questionnaire is used to determine subjective levels of physical activity in each participant.
Time frame
Baseline to one yearSecondary outcomes
1
Cancer related symptoms
Change in Edmonton Symptom Assessment Scale - revised: cancer. Scale is from 0-10, where 0 means the symptom is absent and 10 means the worst possible severity of the symptom is being experienced.
Time frame
Baseline to one year2
Cost-effectiveness
Change in EuroQual - 5Dimensions (EQ-5D) tool - first section is a questionnaire; last section uses a scale from 0-100, where 0 means the worst health imaginable and 100 means the best health imaginable.
Time frame
Baseline to one year3
Fatigue
Change in Functional Assessment of Chronic Illness Therapy - Fatigue subscale - scale is from 0-4, where 0 means "not at all" and 4 means "very much".
Time frame
Baseline to one year4
Quality of life
Single-item measure on quality of life - scale from 0 to 100, where 100 means the best Quality of Life imaginable and 0 means the worst Quality of Life imaginable.
Time frame
Baseline to one yearSponsors and contacts
Click on the lead sponsor to view all of their trials.
University of Calgary
Lead sponsor
University of Alberta
Collaborator
Dalhousie University
Collaborator
Nova Scotia Health Authority
Collaborator
University of Toronto
Collaborator
Centre hospitalier de l'Université de Montréal (CHUM)
Collaborator
University of British Columbia
Collaborator
Memorial University of Newfoundland
Collaborator
University of Prince Edward Island
Collaborator
Alberta Health services
Collaborator
Source ClinicalTrials.gov