Swiss Longitudinal Cohort
ConditionCardiovascular Risk Factors
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age6+
SponsorHypertension Excellence Centre Lucerne
About this trial
The planned research project is a prospective population-based cohort study, similar to the well-known Framingham study in the United States. So far, there is no similar research project in Switzerland.
It is planned to examine of three Swiss municipalities. Recruitment in a first Swiss municipality (Lostallo/Cama GR) started 2014 and ended in 2019. Overall, 496 participants were recruited in this municipality. The five-year follow-up in this municipality started in 2019. It is planned to start recruitment in a second Swiss municipality (Uznach SG) in 2020.
The examinations embrace a broad spectrum of measurements (for details the investigators refer to the published study protocol).
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Resident of Cama GR, Lostallo GR, or Uznach SG
Age ≥6 years (no upper age limit), for voluntary blood sample ≥18 years
Willing to participate in long-term study
Written informed consent (in participants ≥6 years and <18 years signed by parents)
Disqualifiers
No exclusion criteria
Trial population
Population of four Swiss municipalities
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
No intervention
Other intervention
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
Mortality
Time frame
10 yearsSecondary outcomes
1
Cardiovascular events
Cardiovascular events (i.e. stroke, myocardial infarction) will be assessed using questionnaires and case records.
Time frame
10 years2
Heart function
Heart function will be assessed using questionnaires for symptoms, clinical examination and measurement of electromechanical activation time.
Time frame
10 years3
Cognitive function
Cognitive function will be assessed using validated instruments.
Time frame
10 years4
Kidney function
Kidney function will be assessed using laboratory measurements.
Time frame
10 yearsOther outcomes
1
Changes in cardiovascular risk factors
Cardiovascular risk factors will be assessed using validated measurements.
Time frame
10 yearsSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov