Sympatholytic Effects of High Thoracic Erector Spinae Plane Block: Changes in Optic Nerve Sheath Diameter

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-65
SponsorPamukkale University

About this trial

The thoracic erector spinae plane (ESP) block is suggested to potentially affect the stellate ganglion, a key component of the sympathetic nervous system, thereby influencing autonomic functions. Changes in optic nerve sheath diameter (ONSD) are used as indicators of intracranial pressure changes. This study aims to investigate the effects of the ESP block on ONSD, providing insights into its impact on the stellate ganglion and enhancing the understanding of the ESP block's safety and efficacy.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults with neck, shoulder, and arm pain

Those with complex regional pain syndrome

Age between 18-65 years

Both genders

Disqualifiers

Those who refuse procedures and tests

Individuals with conditions that can increase intracranial pressure

Those with severe heart failure

Individuals with second or third-degree atrioventricular block

Trial population

* Adults with neck, shoulder, and arm pain * Those with complex regional pain syndrome The study will include 15 adult patients who are planned to receive T2-ESP block treatment. * Age between 18-65 years * Both genders * ASA physical status I-II

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • thoracic erector spinae plane (ESP) block

    Procedure/Surgery

    The thoracic erector spinae plane (ESP) block is a regional anesthesia technique used for pain management in complex regional pain syndrome. This procedure involves injecting 20 ml of 0.25% bupivacaine into the deep layers of the erector spinae muscles. The patient is positioned appropriately, and the injection site is identified using anatomical landmarks and ultrasound guidance, at the T2 level. A needle is then inserted perpendicularly until it contacts the transverse process, at which point the local anesthetic is administered. The primary objective is to provide significant pain relief.

Treatment groups

15 Participants
are divided into 1 treatment group
Group A: Patients Undergoing Thoracic Erector Spinae Plane Block1 intervention

Trial outcomes

Primary outcomes

1

Optic nerve sheath diameter (ONSD)

To investigate the change in optic nerve sheath diameter (ONSD) following the thoracic erector spinae plane (ESP) block.

Time frame
Before the block and 30 minutes after the block.

Secondary outcomes

1

Pain relief Visual Analog Scale (VAS)

The Visual Analog Scale (VAS) is a tool for measuring pain intensity, using a line marked with "no pain" (0) at one end and "worst pain imaginable" (10) at the other. Patients mark a point on the line that reflects their pain level, and the distance from the "no pain" end to the mark is recorded as the VAS score. This straightforward, subjective measure provides a quantitative assessment of pain, useful for tracking changes over time, evaluating treatment effectiveness, and enhancing communication between patients and healthcare providers.

Time frame
Pain levels will be assessed using the VAS before the block, 30 minutes after the block, and 24 hours later to evaluate the effectiveness of the intervention.
2

Monitoring of Perfusion Index (PI)

The perfusion index (PI) is a numerical value that reflects the pulsatile blood flow in peripheral tissues, measured non-invasively using a pulse oximeter. It indicates the strength of the blood flow at the sensor site, providing valuable information about peripheral perfusion.

Time frame
All perfusion index (PI) values will be measured at 3-minute intervals using 2 pulse oximeter sensors on both the blocked and contralateral unblocked upper extremities up to 30 minutes after local anesthetic injection.

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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