tACS for Sensory Motor Recovery After Stroke
ConditionMotor Recovery
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-75
SponsorThe University of Texas Health Science Center, Houston
About this trial
The overall goal is to investigate the effectiveness of a novel intervention - transcranial alternating current stimulation (tACS) for motor recovery in stroke survivors.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
None
Disqualifiers
Age between 18~75 years old
≥ 6 months post stroke, medically stable;
Unilateral, single stroke (no restriction on type (ischemic or hemorrhagic) or volume (large or small) of stroke);
Visible finger flexor activation/movement
Trial design
Design model
Crossover
Treatments tested in this trial
tACS Sham
DeviceSham tACS will applied to the brain through the scalp for 20 minutes.
tACS 10Hz
Device10Hz tACS will applied to the brain through the scalp for 20 minutes.
tACS 20Hz
Device20Hz tACS will applied to the brain through the scalp for 20 minutes.
Treatment groups
14 Participants
are divided into 3 treatment groupsGroup A: tACS Sham, tACS 10Hz, tACS 20HzExperimental treatment 3 interventions
Group B: HD-tACS 20Hz, HD-tACS 10Hz, HD-tACS ShamExperimental treatment 3 interventions
Group C: HD-tACS 10Hz, HD-tACS 20Hz, HD-tACS ShamExperimental treatment 3 interventions
Trial outcomes
Primary outcomes
1
Block and Box Test (BBT) of Motor functional test
The Box and Block Test (BBT) measures unilateral gross manual dexterity. It is a quick and simple test used with a wide range of populations, including clients with stroke.
Time frame
Change of BBT performance 5 minutes before and 5 minutes after the tACS intervention will be measured.2
EEG alpha band and Beta band
Electroencephalography (EEG) is valuable to infer and evaluate the neural interaction. Components of the alpha and beta frequency bands like the sensorimotor rhythm originated from the primary motor cortex and related brain areas reflect human movement. The power of 8-13 Hz alpha and 14-30 Hz beta frequency bands will be used for the classification.
Time frame
Change of EEG alpha band and Beta band 5 minutes before and 5 minutes after the tACS intervention will be measured.Sponsors and contacts
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Source ClinicalTrials.gov