TAP Block Versus ESP Block in Patients Undergoing Elective Cesarean Section: a Randomized Controlled Trial

Trial statusCompleted
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-45
SponsorUniversity of Padova

About this trial

This study is comparing two types of pain relief techniques-TAP block and ESP block-for women having an elective cesarean section. Both techniques involve injecting local anesthetic under ultrasound guidance to numb nerves and reduce pain after surgery. The TAP block mainly relieves pain in the abdominal wall, while the ESP block may reduce both abdominal wall and deeper, organ-related pain. The main goal is to see if there's a difference in pain at rest six hours after surgery. The study will also look at pain at later time points, the amount of opioid medication needed, how quickly women can walk, and when they start breastfeeding.

A total of 156 women will be randomly assigned to receive one of the two blocks after standard spinal anesthesia. Pain will be measured using a simple 0-10 scale at 6, 12, and 24 hours, both at rest and during movement. The study follows strict ethical rules, ensures patient privacy, and all results-whether positive or negative-will be shared to help improve pain management after cesarean delivery.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age between 18 and 45 years

Elective cesarean section

Ability to provide informed consent

Disqualifiers

Allergy to any of the drugs used in the study

Heart disease with impaired cardiac function

Stage III or higher kidney failure

Coagulation disorders (platelets <100,000/μL or INR >1.5) or severe liver disease

Trial design

Design model

Parallel

Treatments tested in this trial

  • TAP block

    Procedure/Surgery

    TAP block will be performed with with ropivacaine 0.375% 20 mL per side (total 40 mL)

  • ESP block

    Procedure/Surgery

    ESP block will be performed with ropivacaine 0.375% 20 mL per side (total 40 mL)

Treatment groups

90 Participants
are divided into 2 treatment groups
Group A: TAP blockActive comparator 1 intervention
Group B: ESP blockExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Pain at Rest at 6 hours

Pain measured at Rest with Numeric Rating Scale (minimun 0- maximum 10) with 0 meaning no pain and 10 high pain

Time frame
6 hours after end of surgery

Secondary outcomes

1

Pain at Rest at 12 hours

Pain measured at Rest with Numeric Rating Scale (minimun 0- maximum 10) with 0 meaning no pain and 10 high pain

Time frame
12 hours after end of surgery
2

Pain at Rest at 24 hours

Pain measured at Rest with Numeric Rating Scale (minimun 0- maximum 10) with 0 meaning no pain and 10 high pain

Time frame
24 hours after end of surgery
3

Pain at Movement at 6 hours

Pain measured at Rest with Numeric Rating Scale (minimun 0- maximum 10) with 0 meaning no pain and 10 high pain

Time frame
6 hours after end of surgery
4

Pain at Movement at 12 hours

Pain measured at Rest with Numeric Rating Scale (minimun 0- maximum 10) with 0 meaning no pain and 10 high pain

Time frame
12 hours after end of surgery

Other outcomes

Sponsors and contacts

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