About this trial
This study is comparing two types of pain relief techniques-TAP block and ESP block-for women having an elective cesarean section. Both techniques involve injecting local anesthetic under ultrasound guidance to numb nerves and reduce pain after surgery. The TAP block mainly relieves pain in the abdominal wall, while the ESP block may reduce both abdominal wall and deeper, organ-related pain. The main goal is to see if there's a difference in pain at rest six hours after surgery. The study will also look at pain at later time points, the amount of opioid medication needed, how quickly women can walk, and when they start breastfeeding.
A total of 156 women will be randomly assigned to receive one of the two blocks after standard spinal anesthesia. Pain will be measured using a simple 0-10 scale at 6, 12, and 24 hours, both at rest and during movement. The study follows strict ethical rules, ensures patient privacy, and all results-whether positive or negative-will be shared to help improve pain management after cesarean delivery.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age between 18 and 45 years
Elective cesarean section
Ability to provide informed consent
Disqualifiers
Allergy to any of the drugs used in the study
Heart disease with impaired cardiac function
Stage III or higher kidney failure
Coagulation disorders (platelets <100,000/μL or INR >1.5) or severe liver disease
Trial design
Parallel
Treatments tested in this trial
TAP block
Procedure/SurgeryTAP block will be performed with with ropivacaine 0.375% 20 mL per side (total 40 mL)
ESP block
Procedure/SurgeryESP block will be performed with ropivacaine 0.375% 20 mL per side (total 40 mL)
Treatment groups
Trial outcomes
Primary outcomes
Pain at Rest at 6 hours
Pain measured at Rest with Numeric Rating Scale (minimun 0- maximum 10) with 0 meaning no pain and 10 high pain
Secondary outcomes
Pain at Rest at 12 hours
Pain measured at Rest with Numeric Rating Scale (minimun 0- maximum 10) with 0 meaning no pain and 10 high pain
Pain at Rest at 24 hours
Pain measured at Rest with Numeric Rating Scale (minimun 0- maximum 10) with 0 meaning no pain and 10 high pain
Pain at Movement at 6 hours
Pain measured at Rest with Numeric Rating Scale (minimun 0- maximum 10) with 0 meaning no pain and 10 high pain
Pain at Movement at 12 hours
Pain measured at Rest with Numeric Rating Scale (minimun 0- maximum 10) with 0 meaning no pain and 10 high pain
Sponsors and contacts
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