Targeted Decision Making In Renal Cell Carcinoma Relying on a Radiogenomics Translational Platform
ConditionRenal Tumors
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorIRCCS San Raffaele
About this trial
This project aims to provide an accurate strategy to guide the decision making relying on tumor biopsies using standard histology, immunohistochemistry (IHC), spatial transcriptomics, genomics combined with Magnetic Resonance Imaging (MRI) and radiomics. Moreover, the investigators will explore potential markers indicative of response to systemic agents or ablative therapy.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Presence of a renal mass up to 4 cm
Adult > 18 years
Candidate to renal surgery
Informed consent signed
Disqualifiers
Contraindication for MRI
Trial population
subjects with a renal tumor up to 4 cm and candidates for surgery
Trial design
Design model
Other
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
accuracy of multiparametric preoperative MRI
Detection of "Unfavourable outcome" is defined as the presence of at least one of the following pathological characteristics: * High grade tumor (G3 or G4) * Not-organ confined disease (pT3 and or pT4 and/or LNI) * Sarcomatoid features
Time frame
At final pathological assessment , at least 1 month after surgerySponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov