About this trial
The purpose of this study is to compare the effects of high-repetition task-oriented training and high-intensity gait training on walking capacity and functional mobility in individuals with chronic stroke.
Forty-five participants will be randomly assigned to one of three groups: (1) neurodevelopmental treatment (NDT) alone, (2) NDT combined with high-repetition task-oriented training, or (3) NDT combined with high-intensity gait training. All participants will receive treatment 3 days per week for 8 weeks (24 sessions in total). Walking capacity (6-Minute Walk Test) and functional mobility (Timed Up and Go Test, modified Dynamic Gait Index, 10-Meter Walk Test) will be assessed before and after the intervention by an assessor blinded to group allocation. The study hypothesizes that adding structured, intensity-based training approaches to conventional NDT will lead to greater improvements in walking capacity than NDT alone.
Eligibility criteria
Qualifiers
Diagnosis of first-ever unilateral stroke (ischemic or hemorrhagic) confirmed by clinical and/or radiological findings
Time since stroke onset of at least 6 months (chronic phase)
Age between 18 and 75 years
Ability to walk at least 10 meters independently, with or without an assistive device
Disqualifiers
Recurrent stroke or bilateral hemispheric involvement
Unstable cardiovascular disease or other medical conditions contraindicating high-intensity exercise
Severe lower extremity spasticity interfering with gait training (Modified Ashworth Scale score > 3)
Orthopedic, rheumatological, or other neurological conditions affecting gait
Trial design
Treatments tested in this trial
- Neurodevelopmental Treatment
- High-Repetition Task-Oriented Training
- High-Intensity Gait Training
Treatment groups
Sponsors and collaborators
Istanbul University - Cerrahpasa
Lead sponsor
Bingol University
Sponsor institution