About this trial
The goal of this clinical trial is to find out whether a type of electrical brain stimulation, called temporal interference stimulation, can temporarily change the way different parts of the brain communicate with each other.
Participants will:
* Complete two stimulation phases - overnight and during wakefulness * Undergo two MRIs per study phase
Eligibility criteria
Qualifiers
Adults aged 18-50
Medically healthy
U.S. citizen or holding permanent resident status
English-speaking
Disqualifiers
Any current or past history of neurological disorders or acquired neurological disease (e.g. stroke, traumatic brain injury), including intracranial lesions (including clinically significant findings identified in first MRI)
History of inpatient psychiatric hospitalization
History of head trauma resulting in prolonged loss of consciousness; or a history of greater than 3 grade I concussions
Current history of poorly controlled headaches including intractable or poorly controlled migraines
Trial design
Treatments tested in this trial
- Temporal Interference Transcranial electrical stimulation (TI-TES)
- Sham stimulation