Temporal Interference for Thalamocortical Activity and Network Modulation

Trial statusRecruiting
Trial phasePhase 1
Trial typeInterventional
Biological sexAll
Age18-50
SponsorUniversity of Wisconsin, Madison

About this trial

The goal of this clinical trial is to find out whether a type of electrical brain stimulation, called temporal interference stimulation, can temporarily change the way different parts of the brain communicate with each other.

Participants will:

* Complete two stimulation phases - overnight and during wakefulness * Undergo two MRIs per study phase

Eligibility criteria

Qualifiers

Adults aged 18-50

Medically healthy

U.S. citizen or holding permanent resident status

English-speaking

Disqualifiers

Any current or past history of neurological disorders or acquired neurological disease (e.g. stroke, traumatic brain injury), including intracranial lesions (including clinically significant findings identified in first MRI)

History of inpatient psychiatric hospitalization

History of head trauma resulting in prolonged loss of consciousness; or a history of greater than 3 grade I concussions

Current history of poorly controlled headaches including intractable or poorly controlled migraines

Trial design

Treatments tested in this trial

  • Temporal Interference Transcranial electrical stimulation (TI-TES)
  • Sham stimulation

Treatment groups

40 Participants
are divided into 2 treatment groups