Testicular Evaluation of Azoospermia Using Micro-Ultrasound
ConditionAzoospermia
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexMale
Age18+
SponsorPaul Shin
About this trial
The investigation is a small feasibility study to determine whether there are imaging features related to the seminiferous tubules in the testes under microultrasound. The results from this study will provide guidance on the design and power analysis of future studies in this area.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Men with azoospermia confirmed based on semen analysis
Post-vasectomy patients with verified azoospermia after the procedure
Men pre-vasectomy with proven natural fertility or with normal semen analysis
Males assigned at birth over the age of 18
Disqualifiers
History of prior microdissection of the testes
History of hypogonadotropic hypogonadism
Trial population
Participants who meet inclusion and exclusion criteria and have been referred to the study infertility clinic.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
40 Participants
are grouped into 3 trial groupsGroup A: Men with azoospermia confirmed based on semen analysis
Group B: Post-vasectomy patients with verified azoospermia after the procedure
Group C: Men pre-vasectomy with proven natural fertility or with normal semen analysis
Trial outcomes
Primary outcomes
1
The micro-ultrasound imaging procedure produces imaging features which correlate to the presence of sperm within the seminiferous tubules of the testes
The investigation is a small feasibility study to determine whether there are imaging features related to the seminiferous tubules in the testes under microUS. The results from this study will provide guidance on the design and power analysis of future studies in this area.
Time frame
From time of enrollment to end of scanning (45 minutes)Sponsors and contacts
Click on the lead sponsor to view all of their trials.
Paul Shin
Lead sponsor
Shady Grove Fertility Reproductive Science Center
Sponsor institution
Exact Imaging
Collaborator
Source ClinicalTrials.gov