Testing Interventions Designed to Improve How Members of the General Public Follow Instructions to Take Antibiotics

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorImperial College London

About this trial

Antimicrobial resistance (AMR) is a global public health challenge. Due to overuse of antibiotics, bacteria are becoming resistant to antibiotics, which creates infections that can't be treated by modern medicine. To combat AMR, the public need to both know that AMR is an issue and know what actions they can take to address AMR.

When patients are prescribed antibiotics, the information provided (and how this is provided) is likely to be influential on whether they are taken correctly, or if behaviours that contribute to antimicrobial resistance (such as not finishing the course) predominate.

This study, a large online experiment involving 7,000 people across the UK, aims explore the influence of what information and how it is provided. The study looks at different ways of presenting information on antibiotic packets-from clear instructions to warnings and even scannable QR codes with extra details.

The main goals are to see if these changes can help participants understand how to take antibiotics exactly as prescribed. The investigators also want to see if it helps participants understand what antibiotic resistance is and their role in preventing it.

By understanding what works best, the investigators hope to find simple, effective ways to help everyone use antibiotics wisely, protecting these vital medicines for the future.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Adults aged 18 and over

United Kingdom residents

Have passed the attention check at the start of the online survey.

Disqualifiers

Individuals who are not signed up a market research panel and therefore will not have access to the online survey.

Those resident outside the UK.

Those who fail the attention check at the start of the online survey. Individuals aged under 18.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Behavioural Message

    Behavioral

    Participants are presented with an image of an antibiotic packet, that contains information about the behaviour "take antibiotics exactly as prescribed". This can be delivered to participants via a QR code, or a warning message on the packet.

  • Behavioural message + positive framing

    Behavioral

    Participants are presented with an image of an antibiotic packet, that contains information about the behaviour "take antibiotics exactly as prescribed" and information about AMR, framed in a positive manner. This can be delivered to participants via a QR code, or a warning message on the packet.

  • Behavioural message + negative framing

    Behavioral

    Participants are presented with an image of an antibiotic packet, that contains information about the behaviour "take antibiotics exactly as prescribed" and information about AMR, framed in a negative manner. This can be delivered to participants via a QR code, or a warning message on the packet.

Treatment groups

7,000 Participants
are divided into 7 treatment groups

7

Treatment groups

See each treatment group below.

Group A: ControlNo intervention 0 interventions
Group B: Behavioural Message - QR codeExperimental treatment 1 intervention
Group C: Behavioural Message - WarningExperimental treatment 1 intervention
Group D: Behavioural message + positive framing - QR codeExperimental treatment 1 intervention
Group E: Behavioural message + positive framing - WarningExperimental treatment 1 intervention
Group F: Behavioural message + negative framing - QR CodeExperimental treatment 1 intervention
Group G: Behavioural message + negative framing - WarningExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Overall intent to take antibiotics as prescribed

The proportion of Moderately, Very likely, or 'Yes' responses across the 4 measures of intent (taking one dose at a time, taking the full course, spacing the doses throughout the day, stopping when feeling better).

Time frame
During the intervention

Secondary outcomes

1

Proportion of correct responses on comprehension questions about antibiotic use

Responses to six questions relating to taking antibiotics exactly as prescribed, including how many per day, how many days for, when should tablets be taken, duration of course, how many tablets at a time and how to space across day

Time frame
During the intervention

Other outcomes

1

Individual measures of intent to take antibiotics as prescribed

Impact of intervention on individual behaviours relating to taking antibiotics as prescribed

Time frame
During the intervention
2

Do the interventions increase understanding that not taking antibiotics as prescribed contributes to AMR?

Time frame
During the intervention
3

What is the effect of changing the messaging of the intervention on overall intent to take antibiotics as prescribed

Control vs Neutral framing vs positive framing vs negative framing

Time frame
During the intervention
4

What is the effect of changing the mechanism of delivery of the intervention on overall intent to take antibiotics as prescribed

Control vs QR code vs Warning message on packet

Time frame
During the intervention

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Imperial College London

Lead sponsor

The Behavioural Insights Team

Collaborator

This trial is not recruiting at the moment. You can still explore other options: