Testing the Abuse Liability of Hyper-palatable Foods

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18+
SponsorUniversity of Kansas

About this trial

The study will conduct a laboratory study designed to evaluate the rewarding and addictive properties of hyper-palatable foods (HPF), using potato chips as the food stimulus/sample HPF.

Eligibility criteria

Qualifiers

Adults 18+ years old

High dietary intake of regular potato chips (HPF stimulus in the study), identified as >=3 times per week via a standard dietary history questionnaire

Like potato chips, the study-provided food (rating of >6 out of 10 on visual analogue scale) and willing to consume them in the lab.

Disqualifiers

Currently prescribed medications for weight loss (e.g., Ozempic), attention deficit hyperactivity disorder, substance use disorder, or binge eating disorder

Substance use disorder diagnosis in the past year (self-reported) or substantial consequences from substance use in the past year (score on Drug Abuse Screening Test-10 of 6 or higher)

Eating disorder diagnosis in the past year

Bariatric surgery in the past year

Trial design

Treatments tested in this trial

  • Full Dose HPF
  • Modified Dose- No Fat
  • Modified Dose- No Sodium
  • Jicama Root Vegetable Chip- Negative Control

Treatment groups

168 Participants
are divided into 4 treatment groups

Sponsors and collaborators

University of Kansas

Lead sponsor

National Institute on Drug Abuse (NIDA)

Collaborator