About this trial
Autoimmune gastritis is currently relatively rare in China due to its insidious onset, diverse clinical manifestations involving multiple systems such as digestive, hematological, and nervous systems, and its association with other autoimmune diseases. It can also be complicated by hyperplastic gastric polyps, gastric neuroendocrine tumors, gastric adenocarcinoma, and other diseases, making it prone to clinical misdiagnosis. As a form of gastritis in the post-Helicobacter pylori era, its detection rate has been gradually increasing with the continuous improvement of endoscopic technology in China. Applying the PDCA cycle management in disease diagnosis can significantly improve the detection rate of the disease, benefiting patients. Through the PDCA management model, this study further enhanced gastroenterologists' understanding of this disease from various aspects, aiming to improve the clinical diagnosis of autoimmune gastritis.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
None
Disqualifiers
None
Trial population
Endoscopy center gastroenterologists in our hospital in 2024
Trial design
Cohort
Prospective
Treatments tested in this trial
PDCA training
BehavioralImprove diagnostic rate
Treatment groups
Trial outcomes
Primary outcomes
Diagnostic Accuracy of AIG
To diagnose Autoimmune Gastritis (AIG), the following two criteria must be simultaneously met: Endoscopic or histopathological findings, or both, that are consistent with the characteristics of autoimmune gastritis. Positive gastric autoantibody status, including the presence of anti-parietal cell antibodies (PCA) or anti-intrinsic factor antibodies (IFA), or both.
The suspected diagnosis rate of AIG
If only the endoscopic or histopathological findings, or both, are consistent with the characteristics of autoimmune gastritis, but the gastric autoantibody status (anti-parietal cell antibodies or anti-intrinsic factor antibodies) is not confirmed to be positive, then the case should be considered as a suspected case of Autoimmune Gastritis (AIG).
Secondary outcomes
Parietal Cell Antibody(PCA)
PCA is an important indicator in the diagnosis of AIG.
IF-Ab
IFA is an important indicator in the diagnosis of AIG.
Sponsors and contacts
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