Patients born with heart defects often undergo surgical procedures on a heart lung machine. With improvements in medical and surgical management, their survival has significantly improved, but their brain insult has not been paid much attention. This study is to determine the relationship between specific proteins in the blood and brain injury in patients less than 18-year-old undergoing heart surgery.
less than 18 years old
undergoing cardiac surgery with cardiopulmonary bypass at Boston Children's Hospital
undergoing an emergent procedure and do not have more than 1 hour ahead of time to review the consent
patient in a moribund condition American Society of Anesthesiology (ASA 5)
patient with a hematological and/or oncological disease
Jehovah witnesses
Patients less than 18 years old undergoing a cardiac surgical procedure at Boston Children's Hospital with cardiopulmonary bypass.
Cohort
Prospective
Collecting discarded blood samples
Other interventionDiscarded blood samples will be collected from routine clinical labs collected before and after surgery.
Characterization of postoperative neurological impairment
Understand the correlation between measured proinflammatory cytokines and several proteins that are highly expressed in brain cells with postoperative neurological status.
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This trial is not recruiting at the moment. You can still explore other options:
