The Association Between Time in Range With Markers of Endothelial and Cardiovascular Function
ConditionType 1 Diabetes
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age12-80
SponsorAttikon Hospital
About this trial
In this observaltional study, 90 patients aged \>12 years old with T1DM who are on MiniMed 780G system will be included.We aim to investigate the association between time in range (70-140mg/dl) and time in tight range (70-180mg/dl) with markers of endothelial and cardiovascular function.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Clinical diagnosis of type 1 diabetes >1 year prior to consent date. Diagnosis of type 1 diabetes is based on the investigator's judgment; C peptide level and antibody determinations are not required.
HbA1c < 12.5%
Age >7years at the initiation of the system
Multiple Daily Injections (Basal Bolus therapy) with Total daily insulin use of great than 8.0 units per day over a 1-week period
Disqualifiers
None
Trial population
patients aged \>12 years old with T1DM who are on MiniMed 780G system .
Trial design
Design model
Cohort
Time perspective
Cross-sectional
Treatments tested in this trial
MiniMed 780G
Devicepatients aged \>12 years old with T1DM who are on MiniMed 780G
Treatment groups
90 Participants
are divided into 1 treatment groupGroup A: Type 1 Diabetes Mellitus1 intervention
Trial outcomes
Primary outcomes
1
Endothelial glycocalyx
The association between time in range and the thickness of endothelial glycocalyx
Time frame
Baseline2
Pulse wave velocity
The association between time in range and pulse wave velocity
Time frame
Baseline3
Global longitudinal strain
The association between time in range and global longitudinal strain
Time frame
BaselineLocations
Sponsors and contacts
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Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: