Health TrialsbyHealthPanel

The Barts Charity Children's Environmental Health Clinic

ConditionsEnvironmental ExposureHealth BehaviorAsthma in ChildrenEnvironmental Illness
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age4-17
SponsorQueen Mary University of London

About this trial

The study will be based from a newly formed NHS service, the children's environmental health service. Participants will be children with a known chronic respiratory condition. Participants will undergo personal environmental exposure monitoring as well as home environmental assessments, before personalised exposure reports will be provided including a summary of their exposure and advising mitigation strategies based on exposure patterns and behaviours. The monitoring will be repeated after introduction of mitigation strategies. This will allow a comparison of the effectiveness of each method of mitigation.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Parent/Guardian able to provide written informed consent

Disqualifiers

Inability to use the tools and devices in the research study

Trial design

Design model

Single group

Treatments tested in this trial

  • Exposure mitigations

    Behavioral

    Behavioural interventions with an aim to reduce exposure by targeting occurrences of high exposure

Treatment groups

200 Participants
are divided into 1 treatment group
Group A: Pre and post interventionOther 1 intervention

Trial outcomes

Primary outcomes

1

How effective is a specialist NHS environmental health clinic in reducing exposure to environmental contaminants in children with chronic respiratory disease, and what is the change in health outcomes.

Measurement of the concentrations of common air contaminants (PM1, PM2.5, PM5, PM10, VOCs), the GPs location of areas of high concentration and the behaviours of the individual at times of high and low exposure. For each participant, the social and behavioural factors affecting their exposure will be measured using the environmental health questionnaire (type of accommodation, proximity of school and home to main roads, type of cooking fuel and sprays used in the home, presence or absence of damp or mould, and mode and duration of school commute.

Time frame
3 years

Secondary outcomes

1

What is the environmental exposure of children attending the environmental health clinic?

What is the concentration and duration of exposure of common air contaminants over a three day period - PM2.5, PM5, PM10, NO2 and CO2, in children attending the environmental health clinic?

Time frame
3 years
2

Are clinical tests such as salivary cotinine, exhaled carbon monoxide or blood eosinophils useful in screening for children who have a high environmental exposure to pollutants?

Do children who have high or positive results for salivary cotinine, exhaled carbon monoxide or blood eosinophils, have a higher air pollution exposure (concentration and duration of exposure of common air contaminants over a three day period - PM2.5, PM5, PM10, NO2 and CO2)?

Time frame
3 years
3

At which locations and times of day are children exposed to the most air pollution?

When and where are the highest concentrations of air pollution , when measured over a 72 hour period representative of the participants' normal day to day life.

Time frame
3 years
4

Does exposure to indoor and outdoor air pollution follow a repeated pattern each day?

When concentrations of common air contaminants is measured over a three day period, do the peaks in concentration occur at similar times and locations each day?

Time frame
3 years

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Queen Mary University of London

Lead sponsor

Barts & The London NHS Trust

Collaborator

Source ClinicalTrials.gov
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