The Born in Guangzhou Cohort Study (BIGCS) was established to investigate the short- and long-term effects of exposure in early life on health consequences in Guangzhou, China. Data are collected regarding environmental, occupational and lifestyle exposures as well as health outcomes in later life. Biological samples including blood and tissue samples are also collected from the participants.
Pregnant women with <20 weeks of gestation
Pregnant women intended to eventually deliver in Guangzhou Women and Children's Medical Center
Permanent residents or families intended to remain in Guangzhou with their child for ≥3 years
None
Pregnant women attending their first routine antenatal examinations (usually around week 16) and their partners and offsrping
Cohort
Prospective
No intervention
Other interventionNumber of participant with pregnancy outcomes
Including abortion, stillbirth, live birth, preterm birth, low birth weight and birth defects
Neurodevelopment during early childhood
Including adaptive, gross motor, fine motor, language, and social function; assessed using Gesell Developmental Schedules and Ages and Stages Questionnaire
Weight changes during early childhood
Weight changes from birth, 6 weeks, 6 months, 1 year to 3 years
Height changes during early childhood
Height changes from birth, 6 weeks, 6 months, 1 year to 3 years
Changes of body composition during early childhood
Changes of body composition from birth, 6 weeks, 6 months, 1 year to 3 years. Body composition is assessed using Dual Energy X-Ray Absorptiometry
Click on the lead sponsor to view all of their trials.
Guangzhou Women and Children's Medical Center
Lead sponsor
University of Birmingham
Collaborator
