The Cardiac Stress and Electrocardiographic Changes Caused by Lung Cancer Surgery
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorTampere University Hospital
About this trial
Lung cancer surgery causes significant changes in the small circulation as well as changes in the intrathoracic anatomy. The effects of lung cancer surgery on electrocardiography and the cardiac stress associated with the procedures have not been previously extensively studied. The aim of the present study is to ascertain whether modern mini-invasive lung cancer surgery causes changes in the electrocardiogram, and whether these changes are transitory during short-term follow-up. Furthermore, the study aims to describe whether lung cancer surgery causes significant cardiac stress detectable by intraoperative electrocardiography.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Adult patients scheduled for elective lung cancer surgery
Willing to participate in the study
Curatively aimed surgery
Preoperative decision for mini-invasive surgery
Disqualifiers
Participation in any other clinical trial
Previous chronic or paroxysmal atrial fibrillation or atrial flutter
Cardiac pacemaker
History of cardiac conduction disturbances including bundle branch blocks
Trial population
Patients undergoing elective, curatively aimed, primary lung cancer surgery using mini-invasive surgical techniques.
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
Postoperative electrocardiographic p-, R-, and T-wave amplitude changes
Amplitude changes in the 12-lead rest electrocardiography in millimeters, analyzed daily postoperatively.
Time frame
2 weeks2
Postoperative QRS-duration
The duration of the QRS-complex in milliseconds in the electrocardiogram, measured daily postoperatively using 12-lead rest electrocardiogram.
Time frame
2 weeks3
Postoperative PQ-delay
Changes in the PQ-delay in milliseconds in the 12-lead rest electrocardiogram measured daily postoperatively.
Time frame
2 weeks4
Postoperative QT-interval
The duration of QT-interval in milliseconds in the 12-lead rest electrocardiogram measured daily postoperatively.
Time frame
2 weeksSecondary outcomes
1
Postoperative air leak
The presence and duration of (in days) postoperative air leak
Time frame
1 week2
Need for reoperation
Need for reoperation due to for example bleeding.
Time frame
1 weekSponsors and contacts
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Source ClinicalTrials.gov