The Clinical Impact of Serratus Anterior VS. Erector Spinae Plane Block on Pain Management of Tube Thoracostomy in Emergency Department Patients.

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorAssiut University

About this trial

In the emergency department, tube thoracostomy is a common critical procedure to manage symptomatic pleural issues such as pneumothorax and pleural effusion.\[1\] This technique employed to remove air or fluid from the pleural cavity, restore negative intrapleural pressure and let the lungs expand again to help normal cardiopulmonary function to be restored again. \[2\] However, the procedure is often associated with significant pain, with approximately 50% of patients reporting pain levels between 9-10 out of 10 during the intervention, and for pain management emergency physicians have traditionally combined local anesthetics with opioids or anxiolytics. Yet, these methods have notable drawbacks: opioids carry risks of addiction and adverse side effects (e.g., nausea/vomiting, respiratory depression, delirium), while procedural sedation is time-intensive, requires monitoring, and carries risks of complications such as apnea and hypotension.\[3\] Local anesthetic infiltration for pain management can also fail to effectively and evenly target the intercostal nerves responsible for chest wall sensation.\[4\] Ultrasound-guided fascial plane blocks (erector spinae plane and serratus plane blocks) have recently been proposed as targeted alternatives for reliable and extended pain control of tube thoracostomy as each block produces a unique distribution of anesthesia. \[5\] Despite establishing of these techniques for pain control during thoracic surgeries, its application in emergency settings for tube thoracostomy is underexplored enough yet \[6\], a gap explicitly identified in the recent literature.\[4\] Therefore, in this study we evaluate the impact of ESP and SAP block for pain management and overall quality of recovery which practically performed by emergency physicians.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Adults aged ≥18 to =<60 years presenting to the ED requiring tube thoracostomy.

hemodynamically stable (systolic blood pressure ≥90 mmHg).

Able to provide informed consent.

Disqualifiers

Tension pneumothorax or hemodynamic instability requiring immediate tube insertion without time for block performance.

Known allergy or hypersensitivity to local anesthetics.

Infection or cellulitis overlying the intended needle insertion site.

Chronic opioid use/dependence, or substance use disorder that would confound pain and opioid-consumption outcomes.

Trial design

Design model

Parallel

Treatments tested in this trial

  • serratus anterior plane blocks

    Procedure/Surgery

    Ultrasound-guided fascial plane block,serratus plane blocks for reliable and extended pain control of tube thoracostomy using 20-30 mL of bupivacaine 0.25%

  • Erector Spinae Plane Block

    Procedure/Surgery

    Ultrasound-guided fascial plane block,Erector spinae plane block for reliable and extended pain control of tube thoracostomy using 20-30 mL of bupivacaine 0.25%.

Treatment groups

80 Participants
are divided into 2 treatment groups
Group A: SAPBExperimental treatment 1 intervention
Group B: ESPBExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Intraprocedural pain score (NRS 0-10) recorded immediately after tube insertion and pleural fixation.

Time frame
24 HR

Secondary outcomes

1

Total rescue opioid/sedative dose.

Time frame
24 HR
2

Time required to perform the block (needle-in to needle-out).

Time frame
first 24 HR
3

procedure-related complications (pneumothorax, hematoma, local anesthetic systemic toxicity, block failure).

Time frame
first 24 HR

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

This trial is not recruiting at the moment. You can still explore other options: