The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age35-79
SponsorBrigham and Women's Hospital
About this trial
Individuals with rheumatoid arthritis (RA) have up to 2x the risk of having a heart attack compared to someone without RA. The goal of this study is to identify biomarkers that can help us do a better job of identifying individuals at risk before they develop symptoms of heart disease and start preventative treatment earlier.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
RA diagnosed by a rheumatologist
Age 40- 79
≥1 ASCVD risk factor including prediabetes, hypertension, BMI >30, current or history of cigarette smoking
Disqualifiers
Patients on a statin or with a contraindication to statin, on a cholesterol absorption inhibitor, or on a PCSK9 inhibitor
Patients with diabetes mellitus
Pregnancy
Trial population
Adult patients with rheumatoid arthritis, age 40- 79 years, with one cardiovascular risk factor and not on a statin or has a contraindication to statin therapy.
Trial design
Design model
Cohort
Time perspective
Cross-sectional
Treatments tested in this trial
high sensitivity cardiac troponin
Diagnostic testBlood measurement of high sensitivity cardiac troponin
Treatment groups
No treatment groups listed
Trial outcomes
Primary outcomes
1
coronary artery calcium score
Quantified coronary artery calcium score
Time frame
Cross-sectional, at baselineSponsors and contacts
Click on the lead sponsor to view all of their trials.
Brigham and Women's Hospital
Lead sponsor
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Collaborator
Source ClinicalTrials.gov