The extent of hepatic resection for gallbladder cancer can be done from a wedge resection to 4b/5 bisegmentectomy. This study aims to compare the recurrence rates and survival rates between wedge resection group and bisegmentectomy group. Patients with T2 or T3 gallbladder cancer on preoperative CT exam or patients who were pathologically diagnosed as T2 or T3 gallbladder cancer after initial simple cholecystectomy were enrolled. All patients are randomly assigned to wedge resection or bisegmentectomy group. Number of patients in each group is 44. Primary endpoint is recurrence-free-survival rates and overall survival rates.
Patients with T2 or T3 gallbladder cancer on preoperative CT exam
Patients who are pathologically diagnosed as T2 or T3 gallbladder cancer after initial simple cholecystectomy
Peritoneal seeding or distant metastasis
Impossible to resect the cancer radically
Pathologically diagnosed to other malignancy such as adenosquamous carcinoma, sarcoma, etc.
R1 or R2 resection were pathologically diagnosed.
Parallel
wedge resection
Procedure/SurgeryThe extent of hepatic resection is wedge resection of liver including gallbladder fossa
bisegmentectomy
Procedure/SurgeryThe extent of hepatic resection is 4b/5 bisegmentectomy of liver
Survival rates
3year 5 year
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