This research project aims to study the effect of optimal and individualised nutrition to patients with critical illness during the intensive care unit (ICU) and hospital admission, and until six months after admission. The investigators want to describe and compare the usual care with a dietitian-tailored nutrition care. The hypothesis is that dietitian-tailored nutrition care will result in a higher mean energy intake compared to usual care.
Admitted to the intensive care unit for >48 hours.
At least 18 years of age
Permanent living address in Norway
Death is imminent in the next 96 hours or there is a current treatment limitation in place or the patient is unlikely to survive to 180 days due to underlying/chronic illness
Dialysis dependent chronic renal failure
Suspected or known pregnancy
Wheelchair user
Sequential
Nutrition intervention
Other interventionFrequent follow-up from a dietitian during ICU and hospital stay, and after discharge, up to 6 months after ICU admission.
Mean energy intake
Mean energy intake from day 10 to the end of follow-up of 6 months.
Protein intake
Mean protein intake from day 10 to the end of follow-up of 6 months.
Nutrition intake
Energy and protein intake on each measurement point, Energy and protein intake by location (intensive care unit and ward), Energy and protein intake delivered by nutrition therapy
Nutrition risk during overall follow-up
Assessed with Nutrition Risk Screening 2002 (NRS-2002) at all measure time points, where the score 0-2 indicate no nutrition risk, and a score \> 3 indicate nutrition risk.
Nutrition risk during ICU admission
Assessed with the modified Nutrition Risk in Critically Ill (mNUTRIC) score, ranging from a minimum value of 0 and a maximum value of 9. 0-4 points indicate a low malnutrition risk, 5-9 points indicate patients at high nutrition risk which are the most likely to benefit from aggressive nutrition therapy.
ICU stay
Duration of intensive care unit (ICU) stay in survivors and non-survivors
Hospital stay
Duration of hospital stay in survivors and non-survivors
Mortality
Intensive care unit (ICU), in hospital and 30-day, 90-day and 6 months mortality
Effect of energy intake above 20 kcal/kg/dag
Independent of group allocation, an analysis regarding all secondary outcome measures will be performed comparing participants with an energy intake of \>20 kcal/kg/day with participants with \<20 kcal/kg/day
Click on the lead sponsor to view all of their trials.
University Hospital of North Norway
Lead sponsor
The Northern Norway Health Authority
Collaborator
Karolinska University Hospital
Collaborator
