The Effect of Active Exercise on Maintenance Haemodialysis Patients

ConditionRenal Dialysis

Trial statusRecruiting

Trial phaseNot applicable

Trial typeInterventional

Biological sexAll

Age18-75

SponsorYunfeng Xia

About this trial

The goal of this clinical trial is to discuss the effects of physical activity on nutrition, inflammation, muscle metabolism, and the occurrence of cardiovascular and cerebrovascular events in patients with maintenance haemodialysis. The main question it aims to answer is: can exercise improve nutritional and inflammatory status, enhance muscle strength, and reduce the incidence of cardiovascular and cerebrovascular events in patients with maintenance haemodialysis.

Researchers will compared active exercise group to conventional treatment group to see the impact of exercise on maintenance haemodialysis patients.

Participants will:

Choose low-intensity aerobic exercise workouts such as walking (no less than 8,000 steps per day) or jogging, swimming, Tai Chi, etc., according to their individual conditions, for no less than 30 minutes at a time, at least 3 times per week, and the intensity of the exercise should be based on an RPE score of 12 to 16.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

MHD more than 3 months, 3 times per week, 3-4h each time;

Urea clearance index (Kt/V) >1.2;

Stable condition, no serious infection, tumour and cardiovascular disease;

Willing to join the study and sign the informed consent form.

Disqualifiers

Combined with serious heart and lung disease: such as repeated heart failure, severe arrhythmia, unstable angina pectoris, severe pericardial effusion, severe heart valve disease, hypertrophic cardiomyopathy, aortic coarctation, severe emphysema, pulmonary heart disease, severe pulmonary hypertension (average pressure of the pulmonary artery > 55mmHg), etc.;

Combined with chronic joints, muscles, or vascular disease can not be or is not suitable for regular exercise, such as cerebrovascular disease; combined chronic joint, muscle or vascular disease can not or are not suitable for regular exercise, such as cerebrovascular disease sequelae, serious lower limb joint damage, severe myopathy, deep vein thrombosis, etc.;

unwilling to cooperate with the movement of people

Trial design

Design model

Parallel

Treatments tested in this trial

exercise
Behavioral
such as walking, jogging, swimming, Tai Chi, etc. It needs to be at a certain frequency and intensity

Treatment groups

200 Participants

are divided into 2 treatment groups

Group A: exercise groupExperimental treatment 1 intervention

Group B: Control groupNo intervention 0 interventions

Trial outcomes

Primary outcomes

Mid-upper arm circumference of the non-internal fistula side（AC）

Measure the circumference of the non-internal fistula at the midpoint of the upper arm using a soft tape measure, in centimetres

Time frame