About this trial
The aim of this clinical trial is to evaluate the effect of detrusor underactivity on the functional and symptomatic outcomes following transurethral resection of the prostate (TURP) in benign prostatic hyperplasia patients presenting with chronic urinary retention.
The main questions it aims to answer are:
Will they restore spontaneous voiding?
They will be divided into 2 comparative groups (each group 45 patients) based on detrusor contractility.
* Group (A) consists of patients with normal detrusor (bladder contractility index more than 100). * Group (B) consists of patients with underactive detrusor (bladder contractility index less than 100).
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age: more than 50-year-old
Chronic urinary retention secondary to BPH
Prostate size Above 30 and less than 100gm
Disqualifiers
Prostate size over 100 gm and less than 30 gm
Prostatic carcinoma
Urinary bladder carcinoma
Acute urinary retention
Trial design
Parallel
Treatments tested in this trial
transurethral resection of Prostate
Procedure/SurgeryStandard TURP
Treatment groups
Trial outcomes
Primary outcomes
Restore spontaneous voiding
All the included patients in this study are urethral catheter-dependant pre-operatively and have very bad voiding parameters. we will assess how they will benefit after TURP by regaining spontaneous voiding without the need for urethral catheters any more.
Secondary outcomes
Flow rate improvement
uroflowmetry will be done to all patients 3 months post operative and results will be compared
Post voiding residual urine volume decrease
Post voiding residual urine volume will be calculated using ultrasound and results will be compared
Locations
Sponsors and contacts
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This trial is not recruiting at the moment. You can still explore other options: