The Effect of Detrusor Underactivity in Determining Outcomes After Transurethral Resection of the Prostate for Treatment of Benign Prostatic Hyperplasia

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexMale
Age50+
SponsorAin Shams University

About this trial

The aim of this clinical trial is to evaluate the effect of detrusor underactivity on the functional and symptomatic outcomes following transurethral resection of the prostate (TURP) in benign prostatic hyperplasia patients presenting with chronic urinary retention.

The main questions it aims to answer are:

Will they restore spontaneous voiding?

They will be divided into 2 comparative groups (each group 45 patients) based on detrusor contractility.

* Group (A) consists of patients with normal detrusor (bladder contractility index more than 100). * Group (B) consists of patients with underactive detrusor (bladder contractility index less than 100).

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age: more than 50-year-old

Chronic urinary retention secondary to BPH

Prostate size Above 30 and less than 100gm

Disqualifiers

Prostate size over 100 gm and less than 30 gm

Prostatic carcinoma

Urinary bladder carcinoma

Acute urinary retention

Trial design

Design model

Parallel

Treatments tested in this trial

  • transurethral resection of Prostate

    Procedure/Surgery

    Standard TURP

Treatment groups

90 Participants
are divided into 2 treatment groups
Group A: consists of patients with underactive detrusor (bladder contractility index less than 100).Active comparator 1 intervention
Group B: consists of patients with normal detrusor (bladder contractility index more than 100).Active comparator 1 intervention

Trial outcomes

Primary outcomes

1

Restore spontaneous voiding

All the included patients in this study are urethral catheter-dependant pre-operatively and have very bad voiding parameters. we will assess how they will benefit after TURP by regaining spontaneous voiding without the need for urethral catheters any more.

Time frame
3 months

Secondary outcomes

1

Flow rate improvement

uroflowmetry will be done to all patients 3 months post operative and results will be compared

Time frame
3 months
2

Post voiding residual urine volume decrease

Post voiding residual urine volume will be calculated using ultrasound and results will be compared

Time frame
3 months

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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