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The Effect of Dexmedetomidine Versus Lidocaine on Emergence Agitation.

ConditionEmergence Agitation
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorFayoum University

About this trial

The effect of intravenous dexmedetomidine versus intravenous lidocaine on the emergence agitation after endoscopic sinus surgery.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age : 18-60

ASA Physical Status I or II

Elective endoscopic sinus surgery under general anesthesia .

Disqualifiers

Refusal to participate

Mental retardation or inability to communicate

Allergy to anesthetics or study medications .

Chronic use of beta blockers .

Trial design

Design model

Parallel

Treatments tested in this trial

  • Dexmedetomidine

    Drug

    Group (D) recieves Dexmedetomidine bolus 1mcg/kg over 10 minutes before induction of anesthesia followed by continous infusion at 0.4 mcg/kg/h until the end of surgery

  • Lidocaine

    Drug

    Group (L) recieves IV lidocaine 1.5 mg/kg slowly before induction of anesthesia then lidocaine infusion starts at a rate of 2mg/kg/h

Treatment groups

80 Participants
are divided into 2 treatment groups
Group A: Group LActive comparator 1 intervention
Group B: Group DActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Incidence of emergence agitation (EA) .

Incidence of emergence agitation (EA) as measured by Richmond Agitation Sedation Scale (RASS) .

Time frame
Immediate after extubation

Secondary outcomes

1

heart rate (beats per minute )

heart rate (beats per minute ) was measured using standard ECG monitoring

Time frame
baseline ( preoperative )
2

heart rate (beats per minute )

heart rate (beats per minute ) was measured using standard ECG monitoring

Time frame
after 30 minutes ( intraoperative)
3

heart rate (beats per minute)

heart rate (beats per minute ) was measured using standard ECG monitoring

Time frame
after 60 minutes ( intraoperative )
4

heart rate (beats per minute)

heart rate (beats per minute ) was measured using standard ECG monitoring

Time frame
0 hour postoperative

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Fayoum University

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: