The Effect of Frailty on Hypotension After Anesthesia Induction

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age65+
SponsorSelcuk University

About this trial

Frailty is defined as a state of weakness resulting from a decrease in physiological reserves due to physiological changes, diseases, and/or malnutrition associated with advancing age. Frail older adults face increased mortality, morbidity, and healthcare costs when exposed to stressors, making this issue increasingly important. The FRAIL Scale, developed by Morley et al. , is a 5-item measure that assesses frailty. The FRAIL Scale has been validated in many countries and has been proven to be an effective method for detecting frailty. This scale assesses the patient's fatigue, resistance, mobility, weight loss, and other diseases. In the 5-item FRAIL scale, patients receive 0 or 1 point based on their answers, and a total of 0 points is considered non-frail, 1-2 points is considered pre-frail, and \>2 points is considered frail.

Frailty is associated with a higher risk of postoperative complications. Rothenberg and colleagues reported in a study involving more than 400,000 patients that frailty doubles the risk of postoperative complications .

Hypotension following anesthesia induction is a common complication in geriatric patients. Decreased cardiopulmonary reserve with age leads to an exaggerated drop in blood pressure during induction .

In this study, the investigators aimed to determine the effect of frailty level in geriatric patients on hypotension observed after anesthesia induction.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients who do not have difficulty communicating,

have good cognitive function,

scheduled for surgery under general anesthesia

Disqualifiers

Patients admitted for surgery in emergency situations

Patients with active malignancy

Patients with physical disabilities and impairments (limb amputations, stroke sequelae, unable to speak, hearing problems)

Patients with acute infections

Trial population

Patients over the age of 65 undergoing elective surgery under general anesthesia

Trial design

Design model

Case-crossover

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

The effect of fragility level on hypotension observed after anesthesia induction

Time frame
20 minutes

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

This trial is not recruiting at the moment. You can still explore other options: