About this trial
This study will be conducted as a prospective, randomized crossover trial evaluating non-diabetic and pre-diabetic adults ($n=12$) continuously monitored with Dexcom G7 continuous glucose monitors over an 11-day period. Participants will complete two distinct exercise protocols in a randomized sequence: five consecutive days of Zone 2 aerobic exercise and a single session of high-intensity interval training (HIIT). Primary outcome metrics will focus on mean glucose levels and time in range (TIR, defined as $\\le 120\\text{ mg/dL}$) recorded throughout each active exercise block and its associated recovery window. To evaluate the comparative efficacy of the two modalities, paired within-subject differences will be statistically analyzed against pre-specified non-inferiority margins set at $3\\text{ mg/dL}$ for mean glucose, as well as a primary $3$-point and secondary $5$-point margin for time in range.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
None
Disqualifiers
None
Trial design
Crossover
Treatments tested in this trial
High Intensity Interval Training
Other interventionThe Norwegian 4x4: The workout begins with a 5-to-10-minute warm-up, followed by four separate 4-minute high-intensity intervals where you push your body to 85%-95% of your maximum heart rate (roughly an 8 or 9 out of 10 effort level, where you are breathing too heavily to speak full sentences). Each intense "push" is interspersed with a 3-minute active recovery period of low-intensity movement-such as walking or light cycling-to let your heart rate drop back down to roughly 60%-70% of its maximum before starting the next round.
Moderate Intensity aerobic training
Other intervention45 minutes of zone 2 training for five consecutive days
Treatment groups
Trial outcomes
Primary outcomes
Mean Glucose Concentration
Average glucose level recorded by continuous glucose monitor (CGM) across the exercise intervention block and its subsequent recovery window.
Time in Range (TIR)
Percentage of time spent with sensor glucose values under 120mg/dL during the active exercise block and its recovery window.
Sponsors and contacts
Click on the lead sponsor to view all of their trials.
This trial is not recruiting at the moment. You can still explore other options: