In this study, the investigators compared the improvement of immune function related indicators in patients with liver cirrhosis after laparoscopic splenectomy and azygoportal disconnection. To determine whether surgical treatment can help enhance postoperative immune function and improve patient prognosis.
A clinical, radiological or histologic diagnosis of cirrhosis of any etiology
Splenomegaly with secondary hypersplenism
gastroesophageal variceal bleeding
Informed consent to participate in the study
Hepatocellular carcinoma or any other malignancy,
Child-Pugh grade C
Recent peptic ulcer disease
History of Hemorrhagic stroke
Single group
Laparoscopic splenectomy and azygoportal disconnection
Procedure/SurgeryLaparoscopic splenectomy and azygoportal disconnection is performed by the same surgical team.
The immune function CD4+ at 3 months after surgery
The level of the immune function CD4+ at 3 months after surgery
The immune function CD4+ at 6 months after surgery
The level of the immune function CD4+ at 6 months after surgery
The immune function CD4+ at 12 months after surgery
The level of the immune function CD4+ at 12 months after surgery
The immune function CD4+ at 24 months after surgery
The level of the immune function CD4+ at 24 months after surgery
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