the Effect of Nutrition-optimized Prehabilitation on Perioperative Intervention in Primary Liver Carcinoma

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorSecond Affiliated Hospital, Zhejiang University, School of Medicine

About this trial

The aim of this project is to investigate the effect of triple prehabilitation led by nutritional optimization in liver cancer patients' surgery. It improves the preoperative nutritional status of cancer patients, reduces the incidence of early postoperative complications, promotes postoperative recovery, and improves the quality of patients' survival. Patients were randomized into experimental and control groups based on exclusion and inclusion criteria. Nutritional interventions and exercise and psychological interventions for patients. Routine clinical blood tests will be performed at the time of enrollment, on the first day before surgery and on the first, third and fifth days after surgery. Enrolled patients were followed up by telephone or outpatient clinic at 1 month postoperatively.

Eligibility criteria

Qualifiers

Patients diagnosed with primary liver cancer.

Patients between the ages of 18 and 80.

Patients who are feasible for surgical treatment after clinical evaluation.

Disqualifiers

Patients with liver metastases or combined with other tumors.

Patients with allergy to the ingredients of nutritional preparations. ③Patients with severe malnutrition who cannot eat by mouth. ④Patients with hyperthyroidism, fistula, and combined digestive system diseases.

Trial design

Treatments tested in this trial

  • Nutritional optimization-led triple prehabilitation Intervention
  • Conventional triple prehabilitation Intervention

Treatment groups

120 Participants
are divided into 2 treatment groups

Sponsors and collaborators

Second Affiliated Hospital, Zhejiang University, School of Medicine

Lead sponsor

ZhuZhou Central Hospital

Collaborator

Shangrao People's Hospital

Collaborator